科学研究情况简介 |
【近5年主持科研项目】 1. 国家自然科学基金青年基金(2022年-2024年),主持 2. 江苏省自然科学基金青年基金(2021年-2024年),主持 3. 中央高校自主科研计划青年基金(2021年-2022年),主持 【近5年代表性论文】 第一作者及通讯作者论文(#共同第一作者): 1. Su R#, Dong L#, Li Y#, Gao M#, et al. METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis. Nature Cell Biology. 2022, 24: 205-216. (SCI:1区, IF: 28.824) 2. Su R#, Dong L#, Li Y#, Gao M#, et al. Targeting FTO suppresses cancer stem cell maintenance and immune evasion. Cancer Cell. 2020, 38: 1-18. (SCI:1区, IF: 31.743) 3. Gao M, Deng J, Liu F, Fan A, Wang Y, Wu H, Ding D, Kong D, Wang Z, Peer D, Zhao Y*. Triggered ferroptotic polymer micelles for reversing multidrug resistance to chemotherapy. Biomaterials. 2019, 223: 119486. (SCI:1区, IF: 12.479) 4. Gao M, Meng X, Guo X, Zhu J, Fan A, Wang Z, Zhao Y*. All-active antitumor micelles via triggered lipid peroxidation. Journal of Controlled Release. 2018, 286: 381-393. (SCI:1区, IF: 9.776) 5. Tao R#, Gao M#, Liu F, Guo X, Fan A, Ding D, Kong D, Wang Z, Zhao Y*. Alleviating the liver toxicity of chemotherapy via pH-responsive hepatoprotective prodrug micelles. ACS Applied Materials & Interfaces. 2018, 10(26): 21836-21846. (SCI:1区, IF: 9.229) 6. Meng X#, Gao M#, Deng J, Lu D, Fan A, Ding D, et al. Self-immolative micellar drug delivery: The linker matters. Nano Research. 2018, 11(12): 6177-6189. (SCI:1区, IF: 8.897) 7. Gao M, Deng J, Chu H, Tang Y, Wang Z, Zhao Y*, Li G*. Stereoselective stabilization of polymeric vitamin E conjugate micelles. Biomacromolecules. 2017, 18: 4349-4356. (SCI:2区, IF: 6.988) 8. Li X#, Gao M#, Xin K, Zhang L, Ding D, et al. Singlet oxygen-responsive micelles for enhanced photodynamic therapy. Journal of Controlled Release. 2017, 260: 12-21. (SCI:1区, IF: 9.776) 其他作者论文: 1. Qing Y, Dong L, Gao L, Li C, Li H, Prince E, Tan B, Deng X, Wetzel C, Shen C, Gao M, Chen Z, Li W, Zhang B, Braas D, Hoeve J, et al. R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis. Molecular Cell. 2021, 81: 1-18. 2. Su R, Dong L, Li Y, Han L, Gao M, et al. Effective novel Fto inhibitors show potent anti-cancer efficacy and suppress drug resistance. Blood. 2019, 134: 233. 3. Deng J, Liu F, Wang L, An Y, Gao M, Wang Z, Zhao Y*. Hypoxia-and singlet oxygen-responsive chemo-photodynamic micelles featured with glutathione depletion and aldehyde production. Biomaterials Science. 2019, 7(1): 429-441. 4. Chen C, Zhao J, Gao M, Meng X, Fan A, Wang Z, Zhao Y*. Photo-triggered micelles: simultaneous activation and release of microtubule inhibitors for on-demand chemotherapy. Biomaterials Science. 2018, 6: 511-518. 【近5年主要授权专利】 1. 赵燕军、王征、高敏,超稳定纳米药物载体 mPEG-PGlu(D)-VE(D)及制备方法及用途,专利号:CN201610615003.5,授权日:2020.03.17 |